Iron for Erythropoiesis

Iron for erythropoiesis.

Rabbits were rendered anemic by cellular proliferation in response to phlebotomy, by parenteral administraanemia. The total amount of hemoglobin tion of phenyihydrazine and by phlesynthesized was determined by the supbotomy coupled with transfusion of nonply of iron to the marrow and was reviable erythroeytes. Measurements were flected in variations in hemoglobin conmade of the number and iron ...

Erythropoietin, iron, and erythropoiesis.

Recent knowledge gained regarding the relationship between erythropoietin, iron, and erythropoiesis in patients with blood loss anemia, with or without recombinant human erythropoietin therapy, has implications for patient management. Under conditions of significant blood loss, erythropoietin therapy, or both, iron-restricted erythropoiesis is evident, even in the presence of storage iron and i...

Erythropoiesis, erythropoietin, and iron.

Iron supply for erythropoiesis in the rabbit.

Marrow radioiron uptake and marrow blood flow were measured in order to evaluate iron supply for erythropoiesis. Normal, phenylhydrazine-treated and bled animals were studied. The plasma iron turnover of seven normal rabbits was 1.49 +/- 0.22 mg/dl whole blood per d, of 11 rabbits treated 4 d before with phenylhydrazine was 5.16 +/- 1.81, and of four bled animals the plasma iron turnover was 3....

Muscle iron in stress erythropoiesis?

17-92, an oncogenic polycistronic cluster that is targeted by both gene amplifications and deregulated c-MYC, resulting in its overexpression in the “centroblast-like” subgroup of DLBCL. Normally, miR-17-92 is expressed at higher levels in centroblasts compared with naive and memory B cells.4 c-MYC is not normally expressed in GCB cells, suggesting that the differential expression of miR-17-92 ...